ABSTRACT
Introduction: Coronary artery disease (CAD) contributessignificantly to the development of Heart failure in bothdeveloped and developing countries. Recognition of CAD inthese patients significantly alters the management strategy.This study was aimed at assessing the prevalence of coronarydisease in the patient with Left Ventricular systolic dysfunctionof unknown causeMaterial and Methods: This prospective study enrolledall the consecutive patients with LV systolic dysfunction ofunknown cause and Status of coronary arteries of eligiblepatients was assessed with coronary angiogram.Results: A total of 145 patients were enrolled in this study.Mean age of the patients was 53.4±7.43 years. There were91(62.8%) males and 54(37.2%) females. Dyspnea on exertion(DOE) was presenting symptom in 71(51.7%), Angina onexertion (AOE) in 15(10.3%), DOE & AOE in 47(32%), andUnstable angina (UA) in 08(5.5%) of cases. Hypertensionwas the risk factor in 88(60.7%), diabetes in 35(24.13%),smoking in 60(41.4%) and dyslipidemia in 32(22.06%)cases. Echocardiography of study patients revealed, mild LVdysfunction (EF=40%-49%) in 57 (39.7%) patients, moderateLV dysfunction (EF=30%-39%) in 71 (49%) patients andsever LV dysfunction (EF<30%) in 17 (11.7%) patients.Conclusion: coronary artery disease contributes significantlyto development of LV systolic dysfunction of unknown causeand its presence significantly alters the management andprognosis in these patients.